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An atrial septal defect (ASD) is a congenital heart defect where there is a hole in the atrial septum, the wall which separates the right and left atria. A small opening between the two atria (foramen ovale) is always present at birth, but usually seals off shortly thereafter. If the natural opening persists, it is called patent foramen ovale, if the opening is bigger than that and involves a defect in the muscular septum, it is called ASD.
